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Symbol
Name
ID

Prdm8
PR domain containing 8
MGI:1924880

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Spasticity

Spastic tetraparesis

Spastic tetraplegia

Lafora bodies

Ataxia

Progressive cerebellar ataxia

Spastic ataxia

Myoclonus

Dysarthria

Mutism

Paranoia

Psychosis

Hallucinations

Atypical behavior

Cognitive impairment

Confusion

Mental deterioration

Dementia

Hyperreflexia

Seizure

Generalized myoclonic seizure

Disease(s) Associated with PRDM8

progressive myoclonus epilepsy 10

Mouse Phenotypes		nervous system phenotype	abnormal axon guidance	absent corpus callosum	absent hippocampal commissure	increased prepulse inhibition
Availability	Mouse Genotype	nervous system phenotype	abnormal axon guidance	absent corpus callosum	absent hippocampal commissure	increased prepulse inhibition
	Prdm8^tm1Mci/Prdm8^tm1Mci	*
	Prdm8^{em1(IMPC)Wtsi}/Prdm8⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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